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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOK2 All Species: 19.39
Human Site: Y31 Identified Species: 47.41
UniProt: O60496 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60496 NP_003965.2 412 45379 Y31 R R F G A S L Y G G S D C A L
Chimpanzee Pan troglodytes XP_519640 412 45373 Y31 R R F G A S L Y G G S D C A L
Rhesus Macaque Macaca mulatta XP_001114039 206 22378
Dog Lupus familis XP_543259 411 45419 Y31 R R F G A T L Y G E S D C A L
Cat Felis silvestris
Mouse Mus musculus O70469 412 45504 Y34 R R F A A V L Y G E S G C A L
Rat Rattus norvegicus Q4QQV2 480 52151 Y30 K K T W A V L Y P A S P H G V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506018 432 47473 Y31 K R F W A V L Y G E S G S S S
Chicken Gallus gallus A3R064 426 47148 F30 R K I R A Q L F A A S P F G V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998253 575 63920 Y29 K K N W F V L Y P A S Q N G I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792985 602 64705 S30 A K I A K P T S Q V K Y G V L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 46.5 84.2 N.A. 74.5 34.5 N.A. 64.8 33.7 N.A. 33 N.A. N.A. N.A. N.A. 23.9
Protein Similarity: 100 99.5 47.3 87.8 N.A. 79.3 45.2 N.A. 74 48.1 N.A. 44.7 N.A. N.A. N.A. N.A. 35.8
P-Site Identity: 100 100 0 86.6 N.A. 73.3 26.6 N.A. 46.6 26.6 N.A. 20 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 0 93.3 N.A. 73.3 46.6 N.A. 60 46.6 N.A. 40 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 20 70 0 0 0 10 30 0 0 0 40 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 40 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 30 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 30 0 0 0 0 0 % E
% Phe: 0 0 50 0 10 0 0 10 0 0 0 0 10 0 0 % F
% Gly: 0 0 0 30 0 0 0 0 50 20 0 20 10 30 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 30 40 0 0 10 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 80 0 0 0 0 0 0 0 50 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 20 0 0 20 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 10 0 0 10 0 0 0 % Q
% Arg: 50 50 0 10 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 20 0 10 0 0 80 0 10 10 10 % S
% Thr: 0 0 10 0 0 10 10 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 40 0 0 0 10 0 0 0 10 20 % V
% Trp: 0 0 0 30 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 70 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _